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Mathilde Boissel
Curriculum Vitæ
I have robust skills in statistics, modelling and programming. I am passionate about science and technology, and enjoy working in a team to overcome the challenges posed by the healthcare sector.
Professional & Research Experience
Biostatistician / Methodologist
Groupement des Hôpitaux de l’Institut Catholique de Lille (GHICL), DRCI, Méthodology Team
Lomme, France
06/2024 - Today
Activities:
- Methodology: Protocol design, statistical plan, number of subjects (power), randomisation, GIRCI call for proposals expertise.
- Clinical data analysis: Bivariate tests, concordance, survival analysis, modelling (linear, logistic, often mixed for repeated or hierarchical data).
- Quality approach: ISO 9001 certification (in progress), implementation of Github repository & dev {R2Excel} R pkg.
Part-time lecturer
Catholic University of Lille
Lille, France
09/2025 - 01/2026
Activities:
- Lecturer Master 1 Data Managment for Biosciences (FGES), International students (Erasmus). Total hours: 30 hours/year. Biostatistics I.
Biostatistician Engineer
UMR8199 - University of Lille & CNRS
Lille, France
10/2015 - 06/2024
Activities: Statistical studies in genomic, diabete and obesity field
- (Multi)omic analyses: GWAS, DEseq, EWAS, eQTL, mQTL, eQTM, rare variants, PGS, luciferase, MR.
- Methods: Modelling, ANOVA, Classification, Variable/model selection, Dimension reduction (ACP/t-SNE), machine learning and cross-validation, LASSO penalised model.
- Development & Programming: Automated and reproducible processing chains (pipelines, {renv} and {targets}, templates, R packages), visualisations and regular reports (Rmarkdown, Quarto).
- Big data: UKBioBank, All of US, VCF, database access (MongoDB, SQL, Arrow).
- Member of the RIS-CNRS Stat & Geno working group; Supervision (2023/2024) of the biostatistics group (2 to 3 engineers)
Part-time lecturer
University of Lille
Lille, France
09/2020 - 06/2023
Activities:
- Lecturer in the OMICS Master’s programme, MISO and OSB courses. Total hours: 12 hours/year. ANOVA and GLM courses
Intern Modelling a treatment decision-making support
Centre de Traitement des Données - CNO
Caen, France
04/2015 - 09/2015
Activities: Modelling a recommendation system, applied for Hodgkin’s lymphoma patients
- Model combinating survival probabilities and patient ratings on their quality of life and iatrogenic effects, tested by simulation
- Interactive decision-making support (developped with Drupal, WAMP, HTML, PHP)
- Introduction to data managment (Clinsight eCRF and CDISC)
Fixed term contract Project VegeDurable 2
Université de Caen
Caen, France
01/2014 - 04/2014
Activities: Research of the effects of fertilizers, density of soil and water concentration in carrot production
- Statistical modelling and clustering of measures taken in the carrot plot
Intern Estimating of the convolution kernel of the hemodynamic response for the treatment of fMRI data
Cyceron - Site GANIL
Caen, France
05/2014 - 06/2014
Activities: Estimation of parameters of hemodynamic response function
- Introduction to treatment of fMRI data (with R and Matlab), BOLD signal, software SPM, ImageJ
Intern –volontary- Methodologist
Lab COMETE - INSERM - CHU
Caen, France
06/2013 - 06/2013
Activities: Analysis with R and SAS of data about hypovigilance on roads
Education
Trainings during professionnal life
Essais cliniques et Règlement n°536/2014 (Par Sunnikan, Lomme),
Etudes expérimentales en cas unique (SCED) et N-of-1 trials (Par Univ Strasb., Strasbourg),
ANF - Modèles Mixtes de A à Z (Par RIS, CNRS, Oléron),
Devenir auditeur interne selon la norme NF EN ISO 15189 (Par BioConsultants, Lille),
Metabolomics in R (Par Dr. Pietro Franceschi, Physalia Courses),
Mendelian Randomization (Par MRC Biostatistics Unit, Dr Stephen Burgess Univ of Cambridge),
UseR!2019 (Par R Consortium, Toulouse),
CompGen : Computational Genomics Approaches to Precision Medicine (Par Centre Max Delbrück, Berlin)
Different places or on-line
2016 - 2025
Master Degree of Science (M. Sc), in Applied Mathematics “MASS”
University of Caen
Caen, France
2013 - 2015
Speciality: Decision support in business
- Statistics (R, SAS, VBA Excel)
- Computer science (POO Python, MySQL, HTML5, CSS3)
- Mathematics of the decision
- Economic and social sciences (Macro and Micro, Management control, Marketing, Optimization, Supply chain, Project management)
Bachelor Degree of Science (B. Sc), in Applied Mathematics “MASS”
University of Caen
Caen, France
2010 - 2013
Broad-spectrum of knowledge theoretical and practical subjects as statistics, computing, economy, survey and polls, marketing, econometrics, bio-statistics, management control, logistic management…
Scientific Baccalauréat, Speciality: Mathematics
Lycée Le Verrier
Saint-Lô, France
2007 - 2010
Packages
R2Excel: Produce Statistical Tables in R, Save Into (2) Excel File
Mathilde Boissel [aut, cre], Cassandra Chaldaureille [aut, cre], Sahara Graf [aut],
Saïd Maallem [ctb], Laurène Norberciak [aut, cre], Cristian Preda [aut, cre] and Stephane Verdun [aut]
GitHub
déc.. 2024
https://github.com/mboissel/R2Excel/
CARoT: Centralised and Automated RepOrting Tools
mcanouil, mboissel and Ning-L
GitHub
juil.. 2019
https://github.com/mboissel/CARoT/
Oral/Poster communications
Analyse de variants rares issus de données de séquençage à haut débit
Working group RIS Statistics and Genomics
Paris, France
12/10/2018
INTEREST
Sports
Martial art (3y Karv-Maga, 2y Karaté, 2y Jujitsu, 6y Judo), sports needing rigor, respect and humility
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Trips
Renovation work, Photography, Family trips in European big cities, Hike
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Scientific events
Steering committee in a UseR group under construction at Lille; Steering committee in the CNRS working group RIS Statistics and Genomics; “Fête De la Science” at Lille;
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Languages
English (professional, Certification C.L.E.S), French (Mother tongue)
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